Pellegrin J L, Merlio J P, Lacoste D, Barbeau P, Brossard G, Beylot J, Leng B
Clinique de Médecine Interne et Maladies Infectieuses, Hôpital Saint-André, Bordeaux.
Rev Med Interne. 1992 Nov;13(6):438-40. doi: 10.1016/s0248-8663(05)81562-0.
The authors report two cases of hematophagic histiocytosis in HIV positive patients. In the first case, a patient with Kaposi sarcoma and Mycobacterium avium infection had a rapidly deteriorating course with progressive pancytopenia and death, as generally described in the literature. In the second case, hematophagic histiocytosis appeared during HIV primo infection and reversed spontaneously. Although few cases of hemophagocytic syndrome have been reported in HIV positive patient, it could represent an underestimated cause of pancytopenia. Both opportunistic microorganisms and HIV are able to cause hematophagic histiocytosis.
作者报告了两例HIV阳性患者的噬血细胞组织细胞增生症。第一例患者患有卡波西肉瘤和鸟分枝杆菌感染，病程迅速恶化，出现进行性全血细胞减少并死亡，正如文献中普遍描述的那样。第二例患者在初次感染HIV期间出现噬血细胞组织细胞增生症，且自行逆转。尽管HIV阳性患者中报告的噬血细胞综合征病例较少，但它可能是全血细胞减少的一个被低估的原因。机会性微生物和HIV都能够导致噬血细胞组织细胞增生症。
