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1988 - 1990年巴西帕拉州贝伦市男同性恋者和双性恋男性中的艾滋病与艾滋病毒感染情况

[AIDS and HIV infection among homosexual and bisexual men in Belém, Pará, Brazil, 1988-1990].

作者信息

Vasconcelos P F, Macedo O, da Rosa J F, Queiroz B H, de Souza Filho M G, dos Reis R M

机构信息

Serviço de Arbovirus, Instituto Evandro Chagas, Fundação, Nacional de Saúde, Ministério da Saúde, Belém, Pará, Brasil.

出版信息

Rev Latinoam Microbiol. 1992 Oct-Dec;34(4):291-7.

PMID:1345119
Abstract

During three years (1988-1990) blood samples from 307 people were taken to test antibodies for Human Immunodeficiency Virus type 1 (HIV-1) in homo and bisexual males living in Belém, being 149 (48.5%) of the former and 158 (51.5%) of the later. All patients requested examinations spontaneously to find out their status. The ages of tested people ranged from 16 to 64 years old. Serologic diagnosis was made using an enzyme immunoassay (Abbott, São Paulo-Brasil) for screening and an indirect immunofluorescence test (FIOCRUZ, Rio de Janeiro-Brasil) for confirmation. If results were conflicting with these tests, western blot (Du Pont CO. Wilmington-USA) was performed to obtain a definitive result. Sixty-eight (22.1%) of all sera were positive. Although, the positivity in the homosexual group (26.2%) was more higher than in the bisexual group (18.3%). The positivity rate in both groups was directly proportional with the increase of age. Of course, people with less than 20 years old had only 3% of positivity, while between 20-29 had 18.1%, 30-39 had 34.5%, 40-49 had 40% and 50-59 had 50%. The projected curve of positivity, is progressive, that is to say, the risk of homo/bisexual males increases with age and is probably related to increased sexual activity. We conclude that more than one quarter of homosexual men are infected with HIV-1 in Belém.

摘要

在三年时间(1988 - 1990年)里,采集了307人的血样,以检测居住在贝伦的男同性恋者和双性恋男性体内的1型人类免疫缺陷病毒(HIV - 1)抗体,其中前者有149人(48.5%),后者有158人(51.5%)。所有患者均自发要求进行检查以了解自身状况。受测者年龄在16岁至64岁之间。血清学诊断采用酶免疫测定法(雅培公司,巴西圣保罗)进行筛查,并用间接免疫荧光试验(巴西里约热内卢奥斯瓦尔多·克鲁兹基金会)进行确认。如果这些检测结果存在冲突,则进行蛋白免疫印迹法(美国特拉华州威尔明顿杜邦公司)以获得明确结果。所有血清样本中有68份(22.1%)呈阳性。尽管如此,同性恋组的阳性率(26.2%)高于双性恋组(18.3%)。两组的阳性率都与年龄增长成正比。当然,年龄小于20岁的人群阳性率仅为3%,而20 - 29岁人群为18.1%,30 - 39岁人群为34.5%,40 - 49岁人群为40%,50 - 59岁人群为50%。阳性率的预测曲线呈上升趋势,也就是说,男同性恋者和双性恋男性感染HIV - 1的风险随年龄增长而增加,这可能与性活动增加有关。我们得出结论,在贝伦,超过四分之一的男同性恋者感染了HIV - 1。

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