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[口服途径:克氏锥虫的一个进入端口]

[The oral route: an access port for Trypanosoma cruzi].

作者信息

Calvo Méndez M L, Nogueda Torres B, Alejandre Aguilar R

机构信息

Laboratorio de Protozoología, Departamento de Parasitología de la Escuela Nacional de Ciencias Biológicas del I.P.N., México, D.F.

出版信息

Rev Latinoam Microbiol. 1992 Jan-Mar;34(1):39-42.

PMID:1345302
Abstract

Rats and mice were inoculated by oral route with T. cruzi from: 1. Infected mice blood, 2. Experimentally infected triatomines feces, 3. Experimentally infected alive triatomines, and 4. Free cell cultures. Mice showed to be more susceptible to the infection than rats. Mice exhibited to be infected: 30% with blood forms, 85% with triatomines feces, 75% with alive triatomines and 35% with culture forms. Rats exhibited to be infected: 10%, with blood forms, 45% with triatomines feces, 60% with alive triatomines and 25% with culture forms. In both species we observed that metacyclic trypomastigotes originated higher infection percentage than blood and culture forms. With these results we confirm that oral route is a probable way of transmission of T. cruzi and under standardized conditions, it represents a better experimental inoculation route than intraperitoneal route.

摘要

通过口服途径用来自以下来源的克氏锥虫对大鼠和小鼠进行接种

  1. 感染小鼠的血液,2. 实验感染的锥蝽粪便,3. 实验感染的活锥蝽,以及4. 游离细胞培养物。小鼠显示出比大鼠对感染更敏感。小鼠被感染的情况如下:30% 感染血液形态,85% 感染锥蝽粪便,75% 感染活锥蝽,35% 感染培养形态。大鼠被感染的情况如下:10% 感染血液形态,45% 感染锥蝽粪便,60% 感染活锥蝽,25% 感染培养形态。在这两个物种中,我们观察到循环后期锥鞭毛体引发的感染百分比高于血液和培养形态。基于这些结果,我们证实口服途径是克氏锥虫可能的传播方式,并且在标准化条件下,它比腹腔内途径是更好的实验接种途径。

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