Newman K D
Department of Surgery, Children's National Medical Center, Washington, DC 20010.
Semin Pediatr Surg. 1992 May;1(2):145-51.
Malignant liver tumors in children are uncommon but have a high mortality. Survival rates have improved with advances in chemotherapy, imaging, tumor biology, and supportive care. However, complete surgical resection is the cornerstone of successful management. Important determinants of outcome are stage, histology, and resectability. A multidisciplinary team approach to the care of pediatric patients with liver tumors using the latest guidelines from clinical trials provides the best opportunity for care.
儿童恶性肝肿瘤并不常见，但死亡率很高。随着化疗、影像学、肿瘤生物学及支持治疗的进展，生存率有所提高。然而，完整的手术切除是成功治疗的基石。预后的重要决定因素是分期、组织学类型和可切除性。采用来自临床试验的最新指南，多学科团队方法来护理患有肝肿瘤的儿科患者可提供最佳的治疗机会。
