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1
The enzymatic hydrolysis of imidazoleacryloylcholine (murexine) and imidazolepropionylcholine (dihydromurexine) by various cholinesterases.多种胆碱酯酶对咪唑丙烯酰胆碱（墨角藻碱）和咪唑丙酰胆碱（二氢墨角藻碱）的酶促水解作用。
Br J Pharmacol Chemother. 1957 Sep;12(3):320-2. doi: 10.1111/j.1476-5381.1957.tb00141.x.
2
The effect of temperature on the enzymic hydrolysis of choline esters.温度对胆碱酯酶促水解的影响。
Enzymologia. 1959 Sep 1;21:67-74.
3
Interrelationship of murexine, dihydromurexine and human cholinesterases.
Proc Soc Exp Biol Med. 1957 Mar;94(3):500-3. doi: 10.3181/00379727-94-22991.
4
The pharmacological actions of some murexine-like substances.某些类骨螺紫物质的药理作用。
Br J Pharmacol Chemother. 1958 Dec;13(4):378-84. doi: 10.1111/j.1476-5381.1958.tb00224.x.
5
[Reaction of several choline esters with serum cholinesterase].[几种胆碱酯与血清胆碱酯酶的反应]
Z Biol. 1955 Apr;107(6):405-15.
6
[Effect of nucleophiles on the conversion of choline esters under the action of cholinesterase].[亲核试剂对胆碱酯酶作用下胆碱酯转化的影响]
Biokhimiia. 1975 Jan-Feb;40(1):63-70.
7
[Hydrolysis of the cholinergic substance and other choline esters of honey by cholinesterases, and their inhibition in honey].[胆碱酯酶对蜂蜜中胆碱能物质及其他胆碱酯的水解作用及其在蜂蜜中的抑制作用]
Hoppe Seylers Z Physiol Chem. 1955 Jun 30;301(1-2):78-89.
8
[Hydrolysis of dicholine ester of dicarboxylic acids with true cholinesterase and pseudocholinesterase].[二元羧酸二胆碱酯与真性胆碱酯酶和假性胆碱酯酶的水解作用]
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9
The potentiation of histamine by imidazoleacrylcholine (murexine) and imidazolepropionylcholine (dihydromurexine).
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10
Activation on enzymatic hydrolysis of benzoylcholine by tryptamine.色胺对苯甲酰胆碱进行酶促水解时的激活作用。
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引用本文的文献

1
The pharmacological actions of some murexine-like substances.某些类骨螺紫物质的药理作用。
Br J Pharmacol Chemother. 1958 Dec;13(4):378-84. doi: 10.1111/j.1476-5381.1958.tb00224.x.
2
Some pharmacological properties of murexine (urocanoylcholine).海兔毒素（尿刊酰胆碱）的一些药理特性。
Br J Pharmacol Chemother. 1958 Mar;13(1):103-6. doi: 10.1111/j.1476-5381.1958.tb00200.x.

本文引用的文献

1
HYDROLYSIS OF CHOLINE ESTERS BY LIVER.肝脏对胆碱酯的水解作用
Science. 1945 Apr 13;101(2624):385-6. doi: 10.1126/science.101.2624.385.
2
Interrelationship of murexine, dihydromurexine and human cholinesterases.
Proc Soc Exp Biol Med. 1957 Mar;94(3):500-3. doi: 10.3181/00379727-94-22991.
3
The actual nitrogen sources for growth of heterotrophic bacteria in non-limiting media.非限制性培养基中异养细菌生长的实际氮源。
Biochem J. 1956 Sep;64(1):1-6. doi: 10.1042/bj0640001.
4
Identification of pseudocholinesterase in the tissues of ruminants.
Nature. 1955 Oct 22;176(4486):783-4. doi: 10.1038/176783b0.
5
The occurrence of homologues of acetylcholine in ox spleen.牛脾脏中乙酰胆碱同系物的存在。
J Physiol. 1953 Jul;121(1):55-71. doi: 10.1113/jphysiol.1953.sp004930.
6
Identification of murexine as beta-(imidazolyl-(4))-acrylcholine.
Science. 1953 Feb 13;117(3033):161-2. doi: 10.1126/science.117.3033.161.

多种胆碱酯酶对咪唑丙烯酰胆碱（墨角藻碱）和咪唑丙酰胆碱（二氢墨角藻碱）的酶促水解作用。

The enzymatic hydrolysis of imidazoleacryloylcholine (murexine) and imidazolepropionylcholine (dihydromurexine) by various cholinesterases.

作者信息

GRELIS M E, TABACHNICK I I

出版信息

Br J Pharmacol Chemother. 1957 Sep;12(3):320-2. doi: 10.1111/j.1476-5381.1957.tb00141.x.

DOI:10.1111/j.1476-5381.1957.tb00141.x
PMID:13460237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1509698/
Abstract

Several choline esters, including the imidazoleacryloyl and imidazolepropionyl compounds, have been hydrolysed by cholinesterases from various sources. The imidazolepropionyl ester was metabolized by cholinesterases obtained from human plasma, ox spleen, ox serum, and guinea-pig liver, but not by rat liver or bovine red cell cholinesterase. It is suggested the imidazolepropionylcholine or a closely related ester might be the natural substrate for "non-specific" cholinesterase.

摘要

包括咪唑丙烯酰化合物和咪唑丙酰化合物在内的几种胆碱酯已被来自不同来源的胆碱酯酶水解。咪唑丙酰酯可被从人血浆、牛脾脏、牛血清和豚鼠肝脏中获得的胆碱酯酶代谢，但不能被大鼠肝脏或牛红细胞胆碱酯酶代谢。有人提出咪唑丙酰胆碱或一种密切相关的酯可能是“非特异性”胆碱酯酶的天然底物。