Nakamura W, Inada T, Nishimoto Y, Akiba C
C R Seances Soc Biol Fil. 1976;170(2):486-90.
The effects of 2 MeV neutrons were compared with those of 200 kV X-rays for the criterion of lethality in mastocytoma cells of ascites type. The cells prepared as suspension were exposed to the radiations in vitro under aerobic condition and transplanted in the abdominal cavity of mice. Their viability was estimated according to the growing speed of the excreted amount of urinary 5-HIAA in the host animal. The RBE varied between a value of 3.1 at the 10 per cent level of cell survival to 1.8 for the mean lethal dose (Do).
以腹水型肥大细胞瘤细胞的致死率为标准，比较了2兆电子伏中子与200千伏X射线的效应。将制备成悬浮液的细胞在有氧条件下进行体外辐射，并移植到小鼠腹腔内。根据宿主动物尿液中5-羟吲哚乙酸排泄量的增长速度来估计其活力。相对生物效应（RBE）在细胞存活率为10%时的值为3.1，到平均致死剂量（Do）时为1.8之间变化。
