Lamberti J S, Bellnier T, Schwarzkopf S B
Rochester Psychiatric Center, University of Rochester School of Medicine and Dentistry, NY.
Am J Psychiatry. 1992 May;149(5):689-90. doi: 10.1176/ajp.149.5.689.
A retrospective chart review was used to assess weight changes in 36 chronic schizophrenic inpatients who were treated with clozapine after being treated with standard neuroleptics. The average weight gain during 6 months of clozapine treatment was 16.9 lb; 75.0% of the patients gained at least 10 lb. The results confirm previous findings of clozapine-associated weight gain.
通过回顾性病历审查来评估36名慢性精神分裂症住院患者的体重变化，这些患者在接受标准抗精神病药物治疗后使用氯氮平进行治疗。氯氮平治疗6个月期间的平均体重增加为16.9磅；75.0%的患者体重至少增加了10磅。这些结果证实了先前关于氯氮平相关体重增加的研究发现。
