Iro H, Schneider H T, Födra C, Waitz G, Nitsche N, Heinritz H H, Benninger J, Ell C
Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University of Erlangen-Nuremberg, Germany.
Lancet. 1992 May 30;339(8805):1333-6. doi: 10.1016/0140-6736(92)91968-e.
Surgical extirpation of the affected gland has been necessary for cases of sialolithiasis in which the stone cannot be removed by dilatation or dissection of the salivary duct. The ability of the piezoelectric lithotripter to deliver shockwaves to a small focus makes extracorporeal shockwave lithotripsy of salivary gland stones potentially safe. Its safety and efficacy have been assessed in 51 patients with symptomatic solitary salivary stones that could not be removed by conservative measures. The stones had a median diameter of 8 (range 4-18) mm and were located in the submandibular gland in 69% of patients and in the parotid gland in 31%. A total of 72 shockwave treatment sessions (maximum 3 per patient) were given under continuous sonographic monitoring. In 45 patients (88%) complete fragmentation (fragments less than or equal to 3 mm) of the concrements was achieved. No patient needed anaesthesia, sedatives, or analgesics. The only untoward effects were localised petechial haemorrhages after 10 (13%) out of 72 treatments and transient swelling of the gland immediately after delivery of shockwave in 2/72 (3%) sessions. 20 weeks after the first session 90% (46/51) of patients were free of discomfort, and 53% (27/51) were stone free. Stone-clearance rate was higher among patients with stones in the parotid gland (81%) than among those with stones of the submandibular gland (40%). Auxiliary measures such as dilatation or dissection of the salivary duct were required only in patients with stones in the submandibular gland (20%). No long-term damage to the treated salivary gland or to adjacent tissue structures was noted during the median follow-up of 9 (1-24) months. Extracorporeal piezoelectric shockwave therapy seems likely to be safe, comfortable, and effective minimally-invasive, non-surgical treatment for salivary stones.
对于涎石病患者,若结石无法通过唾液腺导管扩张或解剖取出,则需进行患腺手术切除。压电碎石机能够将冲击波传递至小焦点,这使得唾液腺结石的体外冲击波碎石术具有潜在安全性。对51例有症状的孤立性唾液腺结石患者进行了评估,这些结石无法通过保守措施取出。结石的中位直径为8(范围4 - 18)mm,69%的患者结石位于下颌下腺,31%位于腮腺。在持续超声监测下共进行了72次冲击波治疗(每位患者最多3次)。45例患者(88%)结石完全碎裂(碎片小于或等于3 mm)。无需患者麻醉、使用镇静剂或镇痛药。仅有的不良反应是72次治疗中有10次(13%)出现局部瘀点性出血,以及72次治疗中有2次(3%)在冲击波释放后立即出现腺体短暂肿胀。首次治疗20周后,90%(46/51)的患者无不适,53%(27/51)的患者结石消失。腮腺结石患者的结石清除率(81%)高于下颌下腺结石患者(40%)。仅下颌下腺结石患者(20%)需要诸如唾液腺导管扩张或解剖等辅助措施。在9(1 - 24)个月的中位随访期内,未发现对治疗的唾液腺或相邻组织结构有长期损害。体外压电冲击波疗法似乎是一种安全、舒适且有效的唾液腺结石微创非手术治疗方法。