Schoorl W J, van Baar H J, van de Kerkhof P C
Department of Dermatology, University of Nijmegen, The Netherlands.
Acta Derm Venereol. 1992;72(2):141-2.
Several reports suggest that a localized effluvium of scalp hair may occur in patients with psoriasis. The percentages of telogen and catagen hair have been claimed to be normal or increased in isolated cases. In the present study the anagen/telogen ratio was quantified under standardized conditions in psoriatic plaques and uninvolved areas of the scalp in 22 patients and the scalp of 22 normal controls. This assessment was carried out by light microscopic analysis of hair roots, obtained by the hair pluck-method. A consistent increase in the percentages of telogen and catagen hair was shown in psoriatic plaques, compared with the uninvolved areas. Compared with the scalp of normal controls, this percentage was significantly increased in psoriatic plaques, but not in the uninvolved areas.
几份报告表明,银屑病患者可能会出现局部头皮脱发。在个别病例中,休止期和退行期毛发的百分比据称是正常的或有所增加。在本研究中,对22例患者银屑病斑块及头皮未受累区域以及22名正常对照者的头皮,在标准化条件下对生长期/休止期毛发比例进行了量化。该评估通过拔毛法获取发根并进行光镜分析来进行。与未受累区域相比,银屑病斑块中休止期和退行期毛发的百分比持续增加。与正常对照者的头皮相比,银屑病斑块中的这一百分比显著增加,但未受累区域则不然。