Patten S B, Lamarre C J
Department of Community Health Sciences, University of Calgary, Alberta.
Can J Psychiatry. 1992 Apr;37(3):213-5.
Drug-induced depression is classified by the DSM-III-R as an organic mood syndrome of the depressed type. Because drugs have specific pharmacological effects and mechanisms of action, depressive syndromes induced by specific drugs may have characteristic clinical features. An awareness of such features would be valuable for clinical purposes. This review is an attempt to summarize the information on clinical features of drug-induced depressions. The review determined that no unique clinical features have been identified for depressive syndromes associated with most drugs. However, the literature did suggest that depressions associated with oral contraceptive agents may differ significantly from non organic major depressive episodes.
药物性抑郁在《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）中被归类为抑郁型的器质性心境综合征。由于药物具有特定的药理作用和作用机制，特定药物诱发的抑郁综合征可能具有特征性的临床特点。了解这些特点对于临床诊断很有价值。这篇综述旨在总结有关药物性抑郁临床特点的信息。该综述确定，与大多数药物相关的抑郁综合征尚未发现有独特的临床特点。然而，文献确实表明，与口服避孕药相关的抑郁可能与非器质性重度抑郁发作有显著差异。
