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[γ-谷氨酰转移酶与酒精性肝病]

[Gamma-glutamyltransferase and alcoholic hepatic disease].

作者信息

Andrade P, Rocha M L, Sofia C, Pragana M L, Oliveira M R, Portela F, Monteiro G

机构信息

Centro de Gastrenterologia, Faculdade de Medicina, Universidade de Coimbra.

出版信息

Acta Med Port. 1992 Mar;5(3):119-23.

PMID:1350699
Abstract

Accepting the principle that Gama-gt values are elevated in alcoholic patients, the authors attempted to find out if that enzyme might be helpful in distinguishing alcoholics with or without hepatic morphologic lesion. 110 alcoholic patients with and 57 without histologically proved hepatic lesion were studied. The authors conclude that a single determination of Gama-gt lacks specificity to detect, among the alcoholic individuals, those who already carry a morphologic, nonreversible lesion.

摘要

基于γ-GT值在酒精性患者中会升高这一原则,作者试图探究该酶是否有助于区分有或无肝脏形态学病变的酗酒者。对110例有组织学证实的肝脏病变的酗酒患者和57例无肝脏病变的酗酒患者进行了研究。作者得出结论,单次测定γ-GT缺乏特异性,无法在酗酒者中检测出那些已经存在形态学上不可逆病变的患者。

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