T细胞对抗CD3刺激诱导的自杀的敏感性与功能表型无关。
Sensitivity of T cells to anti-CD3-stimulated suicide is independent of functional phenotype.
作者信息
Russell J H, Rush B J, Abrams S I, Wang R
机构信息
Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, MO 63110.
出版信息
Eur J Immunol. 1992 Jun;22(6):1655-8. doi: 10.1002/eji.1830220648.
PMID:1350984
Abstract
We have examined mixed populations and cloned murine CD4+ T cell lines for their sensitivity to anti-CD3-stimulated suicide. The sensitivity of CD4+ clones to anti-CD3-stimulated suicide is independent of their interleukin-2/interleukin-4 or interferon-gamma secretion profile or their lytic efficiency in anti-CD3 redirected lytic assays.
摘要
我们已检测了混合群体以及克隆的小鼠CD4+ T细胞系对抗CD3刺激诱导的细胞自杀的敏感性。CD4+克隆对抗CD3刺激诱导的细胞自杀的敏感性与其白细胞介素-2/白细胞介素-4或干扰素-γ分泌谱无关，也与其在抗CD3重定向杀伤试验中的杀伤效率无关。
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