Rella W, Pawlowsky J, Krepler P, Kummer M
Padiatr Padol. 1976;11(2-2):364-8.
The paper deals with the question how far the lymphocytes of acute lymphatic leukemia patients in remission can be stimulated by PHA and autologous blasts in the MLC-Test. The lymphocyte stimulation by PHA showed considerable variation dependent on the phase of therapy. A significant reduction of the responsiveness to PHA stimulation was found during the prophylactic reinduction treatment with Vincristin and Prednisolon compared with the results during maintenance therapy. The examination of lymphocyte stimulation by conserved autologous blasts in the mixed lymphocyte culture-test yielded positive results in one of three children at the beginning of remission and in 2 of 3 children during the consolidated remission period.
该论文探讨了在混合淋巴细胞培养试验中，缓解期急性淋巴细胞白血病患者的淋巴细胞受PHA和自体胚细胞刺激的程度。PHA对淋巴细胞的刺激显示出很大的差异，这取决于治疗阶段。与维持治疗期间的结果相比，在用长春新碱和泼尼松龙进行预防性再诱导治疗期间，发现对PHA刺激的反应性显著降低。在混合淋巴细胞培养试验中，用保存的自体胚细胞检测淋巴细胞刺激，在缓解期开始时，三个儿童中有一个呈阳性结果，在巩固缓解期，三个儿童中有两个呈阳性结果。
