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脊髓灰质炎病毒在单次和多次感染的HeLa细胞中的吸附与成熟

Adsorption and maturation of poliovirus in singly and multiply infected HeLa cells.

作者信息

DARNELL J E

出版信息

J Exp Med. 1958 May 1;107(5):633-41. doi: 10.1084/jem.107.5.633.

DOI:10.1084/jem.107.5.633
PMID:13525575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2136847/
Abstract

Studies with polio-infected HeLa cells using cell disruption techniques during the early stages of infection have shown that: The inoculum of poliovirus adsorbed on HeLa cells is largely inactivated. Infective virus accumulates in a monolayer sheet of cells in advance of release into the medium. The eclipse period is shorter in multiply infected cells than in those infected with a single particle.

摘要

在感染早期阶段，使用细胞破碎技术对感染脊髓灰质炎病毒的海拉细胞进行的研究表明：吸附在海拉细胞上的脊髓灰质炎病毒接种物大部分被灭活。感染性病毒在释放到培养基之前先在单层细胞中积累。多重感染的细胞中的隐蔽期比单个病毒粒子感染的细胞中的隐蔽期短。

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Adsorption and maturation of poliovirus in singly and multiply infected HeLa cells.脊髓灰质炎病毒在单次和多次感染的HeLa细胞中的吸附与成熟
J Exp Med. 1958 May 1;107(5):633-41. doi: 10.1084/jem.107.5.633.
2
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本文引用的文献

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GENETICS OF SOMATIC MAMMALIAN CELLS : I. DEMONSTRATION OF THE EXISTENCE OF MUTANTS WITH DIFFERENT GROWTH REQUIREMENTS IN A HUMAN CANCER CELL STRAIN (HELA).体细胞的遗传学：I. 在人癌细胞株（Hela）中证明具有不同生长要求的突变体的存在。
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Studies on vaccinia virus. I. The development of hemagglutinating and infective particles in the chorioallantois of the chick embryo.牛痘病毒研究。I. 鸡胚绒毛尿囊膜中血凝性和感染性颗粒的发育
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3
The intracellular growth of bacteriophages. I. Liberation of intracellular bacteriophage T4 by premature lysis with another phage or with cyanide.噬菌体的细胞内生长。I. 用另一种噬菌体或氰化物进行过早裂解以释放细胞内噬菌体T4
J Gen Physiol. 1952 Mar;35(4):645-56. doi: 10.1085/jgp.35.4.645.
4
The measurement of proliferation in tissue cultures by enumeration of cell nuclei.通过细胞核计数来测量组织培养中的细胞增殖。
J Natl Cancer Inst. 1951 Feb;11(4):773-95.
5
Characteristics of the multiplication cycle of pneumonia virus of mice (PVM).小鼠肺炎病毒（PVM）增殖周期的特征
J Exp Med. 1951 Feb;93(2):151-60. doi: 10.1084/jem.93.2.151.
6
Growth characteristics of poliovirus in HeLa cells: nucleic acid metabolism.脊髓灰质炎病毒在海拉细胞中的生长特性：核酸代谢
J Exp Med. 1957 Nov 1;106(5):641-8. doi: 10.1084/jem.106.5.641.
7
Myo-Inositol as an essential growth factor for normal and malignant human cells in tissue culture.肌醇作为组织培养中正常和恶性人类细胞的必需生长因子。
J Biol Chem. 1957 May;226(1):191-205.
8
Virus adsorption and plaque formation in monolayer cultures of trypsin-dispersed monkey kidney.胰蛋白酶分散的猴肾单层培养物中的病毒吸附与蚀斑形成
J Immunol. 1956 Apr;76(4):288-92.
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The maturation of Western equine encephalomyelitis virus and its release from chick embryo cells in suspension.西部马脑炎病毒的成熟及其从悬浮培养的鸡胚细胞中的释放。
J Exp Med. 1955 Feb 1;101(2):205-12. doi: 10.1084/jem.101.2.205.
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One-step growth curve of Western equine encephalomyelitis virus on chicken embryo cells grown in vitro and analysis of virus yields from single cells.西部马脑炎病毒在体外培养的鸡胚细胞上的一步生长曲线及单细胞病毒产量分析
J Exp Med. 1954 Feb;99(2):183-99. doi: 10.1084/jem.99.2.183.