Förstl H, Pohlmann-Eden B, Rothenberger A
Zentralinstitut für Seelische Gesundheit, Mannheim.
Nervenarzt. 1992 Jun;63(6):359-62.
Transient increases of the early cortical somatosensory evoked potentials (SSEP) were observed in 9 patients who received antidepressant and/or neuroleptic treatment. All patients developed myoclonus, and 2 had grand mal seizures. Three cases--one 20-, one 17- and one 15-year-old patient--are presented in detail. Similar observations have been reported in elderly patients. Possible underlying mechanisms and the potential value of the SSEP in identifying and monitoring patients at risk of developing psychotropic drug-induced side-effects are briefly discussed.
在接受抗抑郁药和/或抗精神病药治疗的9例患者中观察到早期皮层体感诱发电位（SSEP）的短暂增加。所有患者均出现肌阵挛，2例发生癫痫大发作。详细介绍了3例患者，分别为1例20岁、1例17岁和1例15岁的患者。在老年患者中也有类似的观察报告。简要讨论了可能的潜在机制以及SSEP在识别和监测有发生精神药物所致副作用风险患者中的潜在价值。
