通过人工PCR-RFLP检测DQB1基因座上胰岛素依赖型糖尿病的易感等位基因。 - Suppr

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超能文献

Detection of susceptibility alleles to insulin-dependent diabetes mellitus at the DQB1 locus by artificial PCR-RFLP.

作者信息

Patel P, Lo Y M, Bell J I, Wainscoat J S

机构信息

Department of Haematology, John Radcliffe Hospital, Headington, Oxford, UK.

出版信息

Immunogenetics. 1992;36(4):264-5. doi: 10.1007/BF00215057.

DOI:10.1007/BF00215057

PMID:1353479

Abstract

摘要

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Detection of susceptibility alleles to insulin-dependent diabetes mellitus at the DQB1 locus by artificial PCR-RFLP.通过人工PCR-RFLP检测DQB1基因座上胰岛素依赖型糖尿病的易感等位基因。

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Assessment of the DQB1-DQA1 complete genotype allows best prediction for IDDM.对DQB1 - DQA1完整基因型的评估能够对胰岛素依赖型糖尿病进行最佳预测。

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HLA-DQ beta 57 in Hispanic patients with insulin-dependent diabetes mellitus.

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J Clin Pathol. 1995 Jan;48(1):33-6. doi: 10.1136/jcp.48.1.33.

本文引用的文献

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus.HLA-DQβ基因与胰岛素依赖型糖尿病的易感性和抗性有关。

Nature. 1987;329(6140):599-604. doi: 10.1038/329599a0.

Modification of enzymatically amplified DNA for the detection of point mutations.用于检测点突变的酶促扩增DNA的修饰

Nucleic Acids Res. 1989 May 11;17(9):3606. doi: 10.1093/nar/17.9.3606.

Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.使用热稳定DNA聚合酶进行引物引导的DNA酶促扩增。

Science. 1988 Jan 29;239(4839):487-91. doi: 10.1126/science.2448875.

Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain.全球范围内I型糖尿病发病率的差异与HLA-DQβ链第57位氨基酸变异有关。

Proc Natl Acad Sci U S A. 1990 Oct;87(19):7370-4. doi: 10.1073/pnas.87.19.7370.

Rapid typing of HLA-DQB1 DNA polymorphism using nonradioactive oligonucleotide probes and amplified DNA.使用非放射性寡核苷酸探针和扩增DNA对HLA - DQB1 DNA多态性进行快速分型。

Immunogenetics. 1991;33(3):163-70. doi: 10.1007/BF01719235.

HLA class II nucleotide sequences, 1991.人类白细胞抗原II类核苷酸序列，1991年。

Immunogenetics. 1991;33(5-6):321-34. doi: 10.1007/BF00216691.

Nomenclature for factors of the HLA system, 1990. The WHO Nomenclature Committee for factors of the HLA system.1990年HLA系统因子命名法。世界卫生组织HLA系统因子命名委员会。

Immunogenetics. 1991;33(5-6):301-9. doi: 10.1007/BF00216689.

Diagnosis of genetic disease by primer-specified restriction map modification, with application to cystic fibrosis and retinitis pigmentosa.通过引物特异性限制图谱修饰诊断遗传疾病，并应用于囊性纤维化和视网膜色素变性。

Lancet. 1991 May 11;337(8750):1115-8. doi: 10.1016/0140-6736(91)92785-z.

Detection of beta-thalassemia using an artificial-restriction fragment length polymorphism generated by the polymerase chain reaction.利用聚合酶链反应产生的人工限制性片段长度多态性检测β地中海贫血。

Nucleic Acids Res. 1991 Feb 25;19(4):959. doi: 10.1093/nar/19.4.959.

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