Hedlund J U, Ortqvist A B, Kalin M, Scalia-Tomba G, Giesecke J
Department of Infectious Diseases, Karolinska Institute, Stockholm, Sweden.
Lancet. 1992 Aug 15;340(8816):396-7. doi: 10.1016/0140-6736(92)91473-l.
Although elderly patients who are admitted to hospital for any disease have a higher risk of pneumonia subsequently, whether those treated in hospital for pneumonia are at even greater risk is unknown. Therefore we retrospectively assessed morbidity and mortality due to pneumonia after discharge in 573 consecutive patients admitted to hospital for pneumonia, gastrointestinal infection, renal infection, or erysipelas. Average follow-up was 34 months. The incidence rate for pneumonia was 5.45 times higher in the group of patients discharged after pneumonia than in the other groups combined (95% confidence interval 2.89-10.26; p less than 0.001), and this group also had more deaths due to pneumonia (p = 0.06). For patients 50 years or older Streptococcus pneumoniae is the main cause of pneumonia. Pneumococcal vaccination after hospital treatment for an episode of pneumonia might be a cost-effective means of preventing disease in this group.
尽管因任何疾病入院的老年患者随后发生肺炎的风险较高,但在医院接受肺炎治疗的患者是否面临更高风险尚不清楚。因此,我们回顾性评估了573例因肺炎、胃肠道感染、肾脏感染或丹毒连续入院的患者出院后因肺炎导致的发病率和死亡率。平均随访时间为34个月。肺炎患者出院组的肺炎发病率比其他组总和高5.45倍(95%置信区间2.89 - 10.26;p < 0.001),且该组因肺炎死亡的人数也更多(p = 0.06)。对于50岁及以上的患者,肺炎链球菌是肺炎的主要病因。肺炎发作后住院治疗后接种肺炎球菌疫苗可能是预防该组疾病的一种具有成本效益的方法。