BHATTACHARYA B K, FELDBERG W
Br J Pharmacol Chemother. 1958 Jun;13(2):156-62. doi: 10.1111/j.1476-5381.1958.tb00211.x.
In cats under chloralose anaesthesia the cerebral ventricles were perfused with Locke solution at a rate of 0.1 ml./min. from an indwelling cannula in the lateral ventricle. The effluent was collected from a cannula either inserted into the cisterna magna or pushed into the aqueduct. When collection was from the cisterna the perfusion included relatively large areas of the subarachnoidal spaces since in cats the foramina of Luschka form the only outlet from the fourth ventricle. Tubocurarine, histamine, and adrenaline injected intravenously caused great variations in outflow from the cisterna, but these changes did not occur when the collection was from the aqueduct. The changes in outflow from the cisterna were similar whether the injection produced a fall of arterial blood pressure as after tubocurarine and histamine, or a rise, as after adrenaline.
在水合氯醛麻醉的猫中，用洛克溶液以每分钟0.1毫升的速度从侧脑室的留置套管灌注脑室。流出液从插入枕大池或推进中脑导水管的套管收集。当从枕大池收集时，灌注包括相对较大面积的蛛网膜下腔，因为在猫中，第四脑室的唯一出口是卢施卡孔。静脉注射筒箭毒碱、组胺和肾上腺素会导致枕大池流出量发生很大变化，但当从导水管收集时，这些变化不会发生。无论注射后是像筒箭毒碱和组胺注射后那样导致动脉血压下降，还是像肾上腺素注射后那样导致动脉血压升高，枕大池流出量的变化都是相似的。
