从肺螺亚纲软体动物非洲大蜗牛的神经节中分离出的贻贝抑制肽类似物。

Mytilus-inhibitory peptide analogues isolated from the ganglia of a pulmonate mollusc, Achatina fulica.

Ikeda T, Yasuda-Kamatani Y, Minakata H, Kenny P T, Nomoto K, Muneoka Y

Faculty of Integrated Arts and Sciences, Hiroshima University, Japan.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1992 Feb;101(2):245-9.

Abstract

Ten peptides that showed an inhibitory effect on phasic contraction of the ABRM of Mytilus were isolated from the ganglia of the African giant snail, Achatina fulica. 2. Seven of the peptides were shown to be hexapeptides having -Pro-Xaa-Phe-Val-NH2 as a common structure, which was previously shown to be a characteristic of Mytilus inhibitory peptides (MIPs). 3. The remaining three were pentadecapeptides, each of which consisted of two MIP-related hexapeptides linked by -Gly-Arg-Arg-.

摘要

从非洲大蜗牛（Achatina fulica）的神经节中分离出10种对紫贻贝前侧缩足肌（ABRM）的相性收缩具有抑制作用的肽。2. 其中7种肽被证明是具有-Pro-Xaa-Phe-Val-NH2共同结构的六肽，该结构先前被证明是贻贝抑制肽（MIPs）的特征。3. 其余3种是十五肽，每种都由两个通过-Gly-Arg-Arg-连接的与MIP相关的六肽组成。