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贻贝抑制肽的结构与作用

Structures and actions of Mytilus inhibitory peptides.

作者信息

Hirata T, Kubota I, Iwasawa N, Takabatake I, Ikeda T, Muneoka Y

机构信息

Faculty of Integrated Arts and Sciences, Hiroshima University, Japan.

出版信息

Biochem Biophys Res Commun. 1988 May 16;152(3):1376-82. doi: 10.1016/s0006-291x(88)80437-6.

DOI:10.1016/s0006-291x(88)80437-6
PMID:3377776
Abstract

Two congeneric peptides that inhibit contraction of the anterior byssus retractor muscle of Mytilus edulis were isolated from the pedal ganglia of the mussel. Their structures were determined to be H-Gly-Ser-Pro-Met-Phe-Val-NH2 and H-Gly-Ala-Pro-Met-Phe-Val-NH2. These hexapeptides also showed inhibitory action on contractions in several other molluscan muscles, such as the cardiac muscle of Meretrix lusoria and the penis retractor muscle of Achatina fulica.

摘要

从贻贝的足神经节中分离出两种抑制紫贻贝前足丝牵缩肌收缩的同属肽。它们的结构被确定为H-Gly-Ser-Pro-Met-Phe-Val-NH2和H-Gly-Ala-Pro-Met-Phe-Val-NH2。这些六肽对其他几种软体动物肌肉的收缩也有抑制作用,如中国蛤蜊的心肌和非洲大蜗牛的阴茎牵缩肌。

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Structures and actions of Mytilus inhibitory peptides.贻贝抑制肽的结构与作用
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Catch-relaxing peptide isolated from Mytilus pedal ganglia.从贻贝足神经节分离出的捕捉放松肽。
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Relaxing and inhibitory actions of pedal ganglion extracts on the anterior byssus retractor muscle of Mytilus.贻贝足神经节提取物对其前足丝牵缩肌的舒张和抑制作用。
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Effects of Mytilus inhibitory peptides on a giant neurone of Achatina fulica Férussac.贻贝抑制肽对非洲大蜗牛巨神经元的影响。
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