Couturier E, Brossard Y, Larsen C, Larsen M, Du Mazaubrun C, Paris-Llado J, Gillot R, Henrion R, Bréart G, Brunet J B
European Centre for the Epidemiological Monitoring of AIDS, Hôpital National de Saint-Maurice, France.
Lancet. 1992 Sep 19;340(8821):707-9. doi: 10.1016/0140-6736(92)92241-7.
The prevalence of HIV infection in women at end of pregnancy, irrespective of outcome, was determined in a comprehensive survey of both women and medical centres during successive 4-week periods in four areas of the Paris region, France. Blood samples were tested anonymously for antibodies to human immunodeficiency virus (HIV)-1 and HIV-2. Of the 11,593 blood samples 0.40% (95% confidence interval [CI] 0.28-0.51) were positive for HIV-1 and 0.02% (95% binomial interval [BI] 0.002-0.065) for HIV-2. Seroprevalence was higher among women with ectopic pregnancy (2%) (95% BI 0.24-7.04); the rate in women having an elective or therapeutic abortion was more than twice that in those delivering babies (0.70% vs 0.28%, p less than 0.05, relative risk 2.54, 95% CI 1.36-4.75). Studies with neonatal HIV seroprevalence as a surrogate for HIV prevalence in pregnant women would underestimate prevalence in these women.
在法国巴黎地区四个区域连续四周对妇女和医疗中心进行的一项综合调查中，确定了妊娠末期妇女中艾滋病毒感染的患病率，无论妊娠结局如何。对血样进行了匿名检测，以检测针对人类免疫缺陷病毒（HIV）-1和HIV-2的抗体。在11593份血样中，0.40%（95%置信区间[CI]0.28-0.51）的HIV-1呈阳性，0.02%（95%二项式区间[BI]0.002-0.065）的HIV-2呈阳性。异位妊娠妇女的血清阳性率较高（2%）（95%BI 0.24-7.04）；进行选择性或治疗性流产的妇女的感染率是分娩妇女的两倍多（0.70%对0.28%，p<0.05，相对风险2.54，95%CI 1.36-4.75）。以新生儿艾滋病毒血清阳性率作为孕妇艾滋病毒感染率的替代指标进行的研究，会低估这些妇女的感染率。
