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[琥珀酰二胆碱及其他胆碱酯对小鼠脊髓的兴奋运动作用]

[Excito-motor action of succinyldicholine and other cholinic esters on the spinal cord of the mouse].

作者信息

Royet-Leblanc M, Gley P

出版信息

C R Seances Soc Biol Fil. 1976 Oct;170(3):548-52.

PMID:135612
Abstract

We have realized on mice the spinal animal experiment, cutting the spinal chord below the bulb during artificial respiration. We have observed that the cholin esters and particularly the succinyldicholin injected into a caudal vein produce muscular contractions, of which we give a graphic. After having discussed these experimental results, we conclude that every cholin ester has an excitatory effect on the spinal chord. It must now be determined which of these esters is the normal medullary transmitter.

摘要

我们已在小鼠身上进行了脊髓动物实验,在人工呼吸时切断延髓下方的脊髓。我们观察到,注入尾静脉的胆碱酯类,尤其是琥珀酰二胆碱,会引起肌肉收缩,我们给出了相关图表。在讨论了这些实验结果后,我们得出结论:每种胆碱酯对脊髓都有兴奋作用。现在必须确定这些酯类中哪一种是正常的髓质递质。

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[Excito-motor action of succinyldicholine and other cholinic esters on the spinal cord of the mouse].[琥珀酰二胆碱及其他胆碱酯对小鼠脊髓的兴奋运动作用]
C R Seances Soc Biol Fil. 1976 Oct;170(3):548-52.
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