Royet-Leblanc M, Gley P
C R Seances Soc Biol Fil. 1979;173(4):692-9.
We have registered contraction of the frog's hyoglossus which is essentially slow. By injecting succinyldicholin in the heart ventricle, we have elicited contractions which prove definitively the motor effect of this cholin ester on the slow muscular fibers. Acetylcholin, injected in the lymph vessels to avoid its effect on the heart, does not contract the hyoglossus. On the contrary, by exciting electrically the hypoglossus nerve, which commands the hyoglossus, we have observed that this mono-ester abolishes the neuro-muscular transmission, as in the curare intoxication. We have found the same phenomenon on the rat's semi-tendinosus which is a slow muscle too. The twitches produced by the ischiaticus are diminished significantly after the injection of acetylcholin in the jugular vein.
我们记录到青蛙舌骨舌肌的收缩，这种收缩本质上是缓慢的。通过向心室注射琥珀酰二胆碱，我们引发了收缩，这明确证明了这种胆碱酯对慢肌纤维的运动效应。将乙酰胆碱注射到淋巴管中以避免其对心脏的影响，舌骨舌肌不会收缩。相反，通过电刺激支配舌骨舌肌的舌下神经，我们观察到这种单酯会像箭毒中毒一样消除神经肌肉传递。我们在大鼠的半腱肌（也是一块慢肌）上也发现了同样的现象。在颈静脉注射乙酰胆碱后，坐骨神经产生的抽搐明显减弱。
