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星形胶质细胞中肾上腺素能受体对氨基酸神经递质摄取的调节

Adrenergic receptor regulation of amino acid neurotransmitter uptake in astrocytes.

作者信息

Hansson E, Rönnbäck L

机构信息

Institute of Neurobiology, University of Göteborg, Sweden.

出版信息

Brain Res Bull. 1992 Sep-Oct;29(3-4):297-301. doi: 10.1016/0361-9230(92)90060-b.

DOI:10.1016/0361-9230(92)90060-b
PMID:1356597
Abstract

Using culture techniques it has been demonstrated that astroglia possess uptake carriers for amino acid neurotransmitters and enzyme systems for inactivation of several neurotransmitters. They express membrane receptors functionally coupled to second messenger systems and they can regulate the extracellular ionic milieu including a clearing of K+ from the extracellular space. With these specific functional characteristics and their strategic anatomy the cells might influence the passage of information between neurons.

摘要

通过培养技术已经证明,星形胶质细胞具有氨基酸神经递质的摄取载体和几种神经递质失活的酶系统。它们表达与第二信使系统功能偶联的膜受体,并且能够调节细胞外离子环境,包括从细胞外空间清除钾离子。凭借这些特定的功能特性及其重要的解剖结构,这些细胞可能会影响神经元之间的信息传递。

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