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疟疾的肾脏受累(作者译)

[Renal involvement in malaria (author's transl)].

作者信息

Weise M, Ehrich J H, Voller A

出版信息

Klin Wochenschr. 1976 Jul 15;54(14):651-60. doi: 10.1007/BF01469144.

Abstract

Malaria infection leads to renal involvement. Reversible proteinuria accompanies many plasmodial infections. Chronic malarial nephrotic syndrome is specifically associated with quartan malaria. Acute renal failure is restricted to infections with Plasmodium falciparum. The pathogenesis of renal involvement during malarial infections includes immunological mechanisms. It is now realized that there exist at least two types of immunological processes: acute transient immune-complex glomerulonephritis with reversible proteinuria and chronic immune-complex glomerulonephritis with irreversible nephrotic syndrome.

摘要

疟疾感染会导致肾脏受累。许多疟原虫感染会伴有可逆性蛋白尿。慢性疟疾肾病综合征与三日疟特别相关。急性肾衰竭仅限于恶性疟原虫感染。疟疾感染期间肾脏受累的发病机制包括免疫机制。现在人们认识到至少存在两种免疫过程:伴有可逆性蛋白尿的急性短暂性免疫复合物肾小球肾炎和伴有不可逆肾病综合征的慢性免疫复合物肾小球肾炎。

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