感染人类三日疟的猴子中的肾病综合征
Nephrotic syndrome in monkey infected with human quartan malaria.
作者信息
Voller A, Draper C C, Shwe T, Hutt M S
出版信息
Br Med J. 1971 Oct 23;4(5781):208-10. doi: 10.1136/bmj.4.5781.208.
Abstract
A splenectomized aotus monkey infected with human quartan malaria (Plasmodium malariae) developed oedema and proteinuria. Histological examination revealed a generalized diffuse glomerulonephritis and immunofluorescent staining showed granular deposits of IgM in the glomeruli. The pathological picture resembled that shown by human patients with the quartan malaria nephrotic syndrome.
摘要
一只感染了人类三日疟（疟原虫属疟原虫）的脾切除绢毛猴出现了水肿和蛋白尿。组织学检查显示为全身性弥漫性肾小球肾炎，免疫荧光染色显示肾小球中有IgM颗粒沉积。病理表现类似于人类三日疟肾病综合征患者所表现出的情况。
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