Goulet J P, Pérusse R, Turcotte J Y
Section of Oral Medicine, School of Dental Medicine, Université Laval, Ste.-Foy, Quebec, Canada.
Oral Surg Oral Med Oral Pathol. 1992 Nov;74(5):692-7. doi: 10.1016/0030-4220(92)90367-y.
This article discusses the relative contraindications to the use of vasoconstrictor in patients currently medicated with tricyclic antidepressants, monoamine oxidase inhibitors, phenothiazines and beta-blockers. It reviews drug interactions and emphasizes potential detrimental systemic effects that epinephrine contained in local anesthetics can have when administered concomitantly with these drugs. Finally, special considerations are expressed concerning patients who abuse illicit drugs such as cocaine.
本文讨论了目前正在服用三环类抗抑郁药、单胺氧化酶抑制剂、吩噻嗪类药物和β受体阻滞剂的患者使用血管收缩剂的相对禁忌证。文章回顾了药物相互作用，并强调了局部麻醉剂中所含肾上腺素与这些药物同时使用时可能产生的潜在有害全身影响。最后，针对滥用可卡因等非法药物的患者提出了特殊注意事项。
