Kurako Iu L, Volianskiĭ V E
Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(4):47-50.
To potentiate the psycho- and autonomic activity of phenazepam and to decrease its side effects, cranio-cervical electrophoresis of the drug is suggested. The method is realized with the aid of a special electrode helmet which permits localizing electrodes in the frontal and occipital areas and at different levels of the lateral surfaces of the neck. Phenazepam in the amount of 1 ml of 3% solution was administered from the cathode. 194 patients with the psychovegetative syndrome in the clinical structure of neurosis or neurosis-like condition were treated. The dynamics of the psycho-vegetative status was verified with the aid of psychometric and vegetative techniques. Cerebral hemodynamics was investigated by rheoencephalography. The data obtained demonstrate that the treatment suggested improves the patients' functional status, decreases reactive anxiety, raises the tempo of sensomotor reactions and attention activity, ameliorates short-term memory, exerts a sympatholytic action, and makes cerebral hemodynamics return to normal. The method produces fewer side effects as compared to the enteral intake of phenazepam.
为增强芬那西泮的精神和自主神经活性并减少其副作用，建议采用该药的颅颈电泳法。该方法借助一种特殊的电极头盔来实现，这种头盔可将电极定位在额部和枕部区域以及颈部侧面的不同水平位置。从阴极给予1毫升3%溶液的芬那西泮。对194例具有神经症或类神经症临床结构中精神植物神经综合征的患者进行了治疗。借助心理测量和植物神经技术来验证精神植物神经状态的动态变化。通过脑血流图研究脑血流动力学。所获得的数据表明，所建议的治疗改善了患者的功能状态，降低了反应性焦虑，提高了感觉运动反应和注意力活动的速度，改善了短期记忆，发挥了抗交感神经作用，并使脑血流动力学恢复正常。与口服芬那西泮相比，该方法产生的副作用更少。
