Schwartz P E
Yale University School of Medicine, Department of Obstetrics and Gynecology, New Haven, CT 06510.
Int J Gynaecol Obstet. 1992 Nov;39(3):175-84. doi: 10.1016/0020-7292(92)90655-3.
To determine the role of prophylactic oophorectomy at elective hysterectomy in the avoidance of ovarian cancer.
A survey was performed of all members of the Society of Gynecologic Oncologists and all obstetrician-gynecologists in the State of Connecticut.
Seventy-nine percent of gynecologic oncologists and 72% of obstetrician-gynecologists surveyed reported 0-1% of women would be saved from ovarian cancer if one ovary was removed at elective hysterectomy at age 45 years. If both ovaries were removed, 8.4% and 32.1% of these physicians respectively responded that 95-100% of women could be saved from ovarian cancer. Approximately 50% responded that macroscopic appearance and frozen section studies at surgery were helpful in deciding whether to remove ovaries at hysterectomy. A literature review suggested that 12% of ovarian cancers might be avoided if women undergo prophylactic oophorectomy at elective hysterectomy.
There is a lack of well-designed epidemiologic studies evaluating risk factors for ovarian cancer and the role of prophylactic oophorectomy at elective hysterectomy.
确定择期子宫切除术中预防性卵巢切除术在预防卵巢癌方面的作用。
对妇科肿瘤学会的所有成员以及康涅狄格州的所有妇产科医生进行了一项调查。
接受调查的79%的妇科肿瘤学家和72%的妇产科医生报告称，如果在45岁进行择期子宫切除术时切除一侧卵巢，0 - 1%的女性可免于患卵巢癌。如果切除双侧卵巢，分别有8.4%和32.1%的这些医生回应称，95 - 100%的女性可免于患卵巢癌。约50%的人回应称，手术中的肉眼外观和冰冻切片检查有助于决定在子宫切除术中是否切除卵巢。一项文献综述表明，如果女性在择期子宫切除术中接受预防性卵巢切除术，12%的卵巢癌可能得以避免。
缺乏设计良好的流行病学研究来评估卵巢癌的危险因素以及择期子宫切除术中预防性卵巢切除术的作用。
