Vlaisavljevic V, Kovacic B, Gavric V
Department of Gynecology, Maribor Teaching Hospital, Slovenia.
Int J Gynaecol Obstet. 1992 Nov;39(3):227-31. doi: 10.1016/0020-7292(92)90661-2.
Programmed oocyte retrieval was performed in order to make the in vitro fertilization (IVF) program cheaper and work of the IVF team easier.
In a group of 77 patients included in the IVF program, the menstrual cycle was modified with estrogen-progesterone contraceptive pills. For this reason, it was possible to start the stimulation protocol in all patients on the same day. The stimulation protocol was a combination of clomiphene (100 mg) for 5 days and HMG (150 IU) every other day. Cycles were monitored by ultrasound only.
The implantation rate per embryo transfer was 22.4%. The number of embryos per embryo transfer was low (2.6 +/- 1.4) and eliminated the need for cryopreservation. Fertilization rate (82%) and embryo transfer rate (87%) were high. The take home baby rate was 14.3%.
Seventy percent of all punctures were performed in 3 days in the middle of the week. In our conditions, programmed oocyte retrieval is associated with significant economic benefits.
进行程序化取卵,以使体外受精(IVF)程序成本更低,且使IVF团队的工作更轻松。
在一组纳入IVF程序的77例患者中,使用雌激素 - 孕激素避孕药改变月经周期。因此,所有患者都能够在同一天开始刺激方案。刺激方案为克罗米芬(100毫克)连用5天,隔天使用人绝经期促性腺激素(HMG,150国际单位)。仅通过超声监测周期。
每次胚胎移植的着床率为22.4%。每次胚胎移植的胚胎数量较少(2.6±1.4),无需进行冷冻保存。受精率(82%)和胚胎移植率(87%)较高。抱婴回家率为14.3%。
70%的穿刺操作在一周中间的3天内完成。在我们的条件下,程序化取卵具有显著的经济效益。