Soni S D, Mallik A, Reed P, Gaskell K
Clinical Psychiatry Research Unit, University of Manchester School of Medicine, Hope Hospital, Salford, United Kingdom.
Hosp Community Psychiatry. 1992 Dec;43(12):1233-8. doi: 10.1176/ps.43.12.1233.
Clinical differences between stable, chronic schizophrenic patients with long stays in the hospital and schizophrenic patients living in the community were investigated. Patients were matched for age, gender, and diagnosis. Hospitalized patients had more severe thought disorder and negative symptoms, and those in the community had a significantly higher incidence of depression and anxiety. The community-based patients were also receiving higher doses of neuroleptic drugs and had a higher incidence and severity of extra-pyramidal side effects. Results suggest that living in the community, despite its obvious benefits, may have its price in terms of the distressing effects of affective symptoms and neuroleptic side effects.
对长期住院的稳定型慢性精神分裂症患者与社区生活的精神分裂症患者之间的临床差异进行了调查。患者在年龄、性别和诊断方面进行了匹配。住院患者有更严重的思维障碍和阴性症状，而社区患者的抑郁和焦虑发生率显著更高。社区患者还接受更高剂量的抗精神病药物治疗，锥体外系副作用的发生率和严重程度也更高。结果表明，尽管生活在社区有明显益处，但在情感症状和抗精神病药物副作用的困扰方面可能要付出代价。
