腐胺掺入与网织红细胞摄取转铁蛋白的关系。

The relationship of putrescine incorporation to transferrin uptake by reticulocytes.

作者信息

Katoh S, Ishii Y, Kohno H, Ohkubo Y

机构信息

Department of Radiopharmacy, Tohoku College of Pharmacy, Sendai, Japan.

出版信息

Res Commun Chem Pathol Pharmacol. 1992 Oct;78(1):125-8.

PMID:1361069

Abstract

We previously reported that putrescine incorporation occurred during transferrin uptake by rat reticulocytes (1). Both the putrescine incorporation and transferrin uptake were enhanced by the presence of Ca2+ and A23187. Furthermore, putrescine dose-dependently increased the transferrin uptake. Additionally, transglutaminase inhibitors partially blocked not only the putrescine incorporation but also the transferrin uptake.

摘要

我们之前报道过，腐胺掺入发生在大鼠网织红细胞摄取转铁蛋白的过程中(1)。Ca2+和A23187的存在增强了腐胺掺入和转铁蛋白摄取。此外，腐胺剂量依赖性地增加了转铁蛋白摄取。另外，转谷氨酰胺酶抑制剂不仅部分阻断了腐胺掺入，还部分阻断了转铁蛋白摄取。