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Reactions of dextrans with antiserums of rabbits immunized with S. typhi.葡聚糖与用伤寒沙门氏菌免疫的兔抗血清的反应。
Proc Soc Exp Biol Med. 1951 Nov;78(2):537-40. doi: 10.3181/00379727-78-19132.
2
Similarities in the mechanisms determining the Arthus and Shwartzman phenomena.决定阿瑟斯现象和施瓦茨曼现象的机制中的相似性。
J Exp Med. 1951 Oct;94(4):347-58. doi: 10.1084/jem.94.4.347.
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[Hemorrhagic phenomena in dermatology].[皮肤病学中的出血现象]
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Studies on the mechanism of the Shwartzman phenomenon; certain factors involved in the production of the local hemorrhagic necrosis.施瓦茨曼现象的机制研究；局部出血性坏死产生过程中的某些相关因素。
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A clinical and experimental study of agammaglobulinemia.无丙种球蛋白血症的临床与实验研究
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6
Alterations in the blood coagulation system induced by bacterial endotoxins. II. In vitro.细菌内毒素引起的血液凝固系统改变。II. 体外实验
J Exp Med. 1958 Mar 1;107(3):369-76. doi: 10.1084/jem.107.3.369.
7
Disturbances in gamma globulin synthesis as experiments of nature.作为自然实验的γ球蛋白合成紊乱
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8
Glycogen, an immunologically specific polysaccharide.糖原，一种具有免疫特异性的多糖。
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9
Studies of the effect bacterial endotoxins on rabbit leucocytes. II. Development of acquired resistance.细菌内毒素对兔白细胞作用的研究。II. 获得性抗性的发展。
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抗原-抗体相互作用对血液凝固的影响。

An effect of antigen-antibody interaction on blood coagulation.

作者信息

ROBBINS J, STETSON C A

出版信息

J Exp Med. 1959 Jan 1;109(1):1-8. doi: 10.1084/jem.109.1.1.

DOI:10.1084/jem.109.1.1
PMID:13611160
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2136934/
Abstract

Each of several antigen-antibody systems studied has been found to affect the coagulation mechanism in the rabbit, causing a marked shortening of the coagulation time in vitro of samples of whole blood maintained in siliconized glassware. Addition of specific antigen to the blood of actively immunized animals or addition of antigen-antibody mixtures to the blood of normal animals produced the effect. The coagulation time of plasma was not affected, indicating that the phenomenon may be mediated by an effect on platelets. This effect of antigen-antibody interaction may be involved in the production of tissue damage in vivo.

摘要

在所研究的几个抗原 - 抗体系统中，每个系统都已被发现会影响兔子的凝血机制，导致保存在硅化玻璃器皿中的全血样本在体外的凝血时间显著缩短。向主动免疫动物的血液中添加特异性抗原，或向正常动物的血液中添加抗原 - 抗体混合物，都会产生这种效果。血浆的凝血时间不受影响，这表明该现象可能是由对血小板的作用介导的。抗原 - 抗体相互作用的这种效应可能参与了体内组织损伤的产生。