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通过注射睾丸诱导雌性豚鼠不育。

Sterility in female guinea pigs induced by injection with testis.

作者信息

ISOJIMA S, GRAHAM R M, GRAHAM J B

出版信息

Science. 1959 Jan 2;129(3340):44. doi: 10.1126/science.129.3340.44.

DOI:10.1126/science.129.3340.44
PMID:13615322
Abstract

Adult virgin female guinea pigs were injected with an emulsion of homologous adult testis and Freund's adjuvant before exposure to males. The fertility of this group was only 24 percent while the fertility of the control group was 84 percent. The testis-injected guinea pigs had also a high titer of antibodies against testis.

摘要

成年未交配的雌性豚鼠在与雄性接触前，被注射了同源成年睾丸乳剂和弗氏佐剂。该组的生育力仅为24%，而对照组的生育力为84%。注射睾丸的豚鼠还具有高滴度的抗睾丸抗体。

相似文献

1
Sterility in female guinea pigs induced by injection with testis.通过注射睾丸诱导雌性豚鼠不育。
Science. 1959 Jan 2;129(3340):44. doi: 10.1126/science.129.3340.44.
2
MECHANISM OF EXPERIMENTAL STERILITY INDUCED IN GUINEA PIGS BY INJECTION OF HOMOLOGOUS TESTIS AND SPERM. II. RELATIONSHIP BETWEEN STERILITY AND A SPERM-IMMOBILIZING ANTIBODY.注射同种睾丸和精子诱导豚鼠实验性不育的机制。II. 不育与精子制动抗体之间的关系。
Fertil Steril. 1964 Mar-Apr;15:213-21. doi: 10.1016/s0015-0282(16)35170-6.
3
Fertility of male guinea-pigs immunized with testicular antigen in Freund's incomplete adjuvant.用弗氏不完全佐剂中的睾丸抗原来免疫的雄性豚鼠的生育力。
Clin Exp Immunol. 1973 Feb;13(2):225-30.
4
MECHANISM OF EXPERIMENTAL STERILITY INDUCED IN GUINEA PIGS BY INJECTION OF HOMOLOGOUS TESTIS AND SPERM. I. RELATIONSHIP BETWEEN STERILITY AND ANAPHYLACTIC REACTION OF THE UTERUS.注射同种睾丸和精子诱导豚鼠实验性不育的机制。I. 不育与子宫过敏反应之间的关系。
Fertil Steril. 1964 Mar-Apr;15:206-12. doi: 10.1016/s0015-0282(16)35169-x.
5
Cytophilic activity in experimental immunologic orchitis in guinea pigs.豚鼠实验性免疫性睾丸炎中的嗜细胞活性。
Fertil Steril. 1976 Jan;27(1):21-7.
6
[Study of immunology and sterility with reference to sperm, seminal fluid and the testicles].[关于精子、精液和睾丸的免疫学与不育症研究]
Nihon Sanka Fujinka Gakkai Zasshi. 1966 Aug;18(8):849-58.
7
Effects of immunization with Freund's complete adjuvant and isologous spermatozoa on the seminiferous epithelium and blood-testis barrier in guinea pigs.弗氏完全佐剂和同种精子免疫对豚鼠生精上皮及血睾屏障的影响。
Anat Rec. 1981 Feb;199(2):197-211. doi: 10.1002/ar.1091990205.
8
AUTOIMMUNE DAMAGE OF THE TESTES INDUCED WITH CHEMICALLY MODIFIED ORGAN SPECIFIC ANTIGEN.化学修饰的器官特异性抗原诱导的睾丸自身免疫损伤。
Folia Biol (Praha). 1964;10:261-7.
9
[Aspermatogenesis in guinea pigs induced by sensitization with homologous testicular antigens].[同源睾丸抗原致敏诱导豚鼠无精子发生]
Arq Bras Endocrinol Metabol. 1965 Aug;14(2):101-17.
10
TRANSVAGINAL IMMUNIZATION OF THE GUINEA PIG WITH HOMOLOGOUS TESTIS AND EPIDIDYMAL SPERM.用同源睾丸和附睾精子对豚鼠进行经阴道免疫接种。
Int J Fertil. 1963 Oct-Dec;8:829-34.

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