Wadhwa N K, Mendelson W B
Dept. of Medicine, State University of New York, Stony Brook.
Adv Perit Dial. 1992;8:195-8.
To compare sleep-disordered respiration in ESRD patients receiving peritoneal dialysis and hemodialysis.
Subjective and objective measures of sleep were recorded in two groups of ESRD patients receiving PD and HD.
Tertiary-referral university hospital
Fifteen PD patients (12 males, 3 females) and 15 HD patients (11 males, 4 females) were studied for two nights in the sleep laboratory.
Ten of the 15 PD patients and 8 of the 15 HD patients reported multiple types of sleep difficulties (NS). In the PD group, seven described substantial difficulty initially going to sleep; ten were troubled by awakenings during the night, while seven suffered from daytime sleepiness. In the HD group, seven described substantial difficulty initially going to sleep; eight were troubled by awakenings during the night, while five experienced day-time sleepiness. No significant difference was observed in total sleep time, intermittent wake time, sleep latency, sleep efficiency, total disordered breathing events, minimum oxygen saturation and periodic leg movements between the PD and HD groups. Sleep apnea was noted in 9 of 15 PD and 8 of 15 HD patients.
This study indicates that the incidence and severity of sleep apnea is similar in ESRD patients receiving chronic peritoneal dialysis and hemodialysis.
比较接受腹膜透析和血液透析的终末期肾病(ESRD)患者的睡眠呼吸障碍情况。
对两组接受腹膜透析(PD)和血液透析(HD)的ESRD患者进行睡眠的主观和客观测量记录。
三级转诊大学医院
15名腹膜透析患者(12名男性,3名女性)和15名血液透析患者(11名男性,4名女性)在睡眠实验室接受了两晚的研究。
15名腹膜透析患者中有10名,15名血液透析患者中有8名报告有多种睡眠困难(无显著性差异)。在腹膜透析组中,7人表示入睡初期存在严重困难;10人夜间易醒,7人白天嗜睡。在血液透析组中,7人表示入睡初期存在严重困难;8人夜间易醒,5人白天嗜睡。腹膜透析组和血液透析组在总睡眠时间、间歇性觉醒时间、睡眠潜伏期、睡眠效率、总呼吸紊乱事件、最低血氧饱和度和周期性腿部运动方面未观察到显著差异。15名腹膜透析患者中有9人、15名血液透析患者中有8人被发现有睡眠呼吸暂停。
本研究表明,接受慢性腹膜透析和血液透析的终末期肾病患者睡眠呼吸暂停的发生率和严重程度相似。