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腹膜透析和血液透析患者的健康相关生活质量、睡眠质量及抑郁状况

Health-related qualıty of lıfe, sleep qualıty, and depressıon in peritoneal dialysis and hemodıalysıs patıents.

作者信息

Turkmen Kultigin, Yazici Raziye, Solak Yalcin, Guney Ibrahim, Altintepe Lutfullah, Yeksan Mehdi, Tonbul Halil Zeki

机构信息

Department of Nephrology, Selcuk University Meram School of Medicine, Konya, Turkey.

出版信息

Hemodial Int. 2012 Apr;16(2):198-206. doi: 10.1111/j.1542-4758.2011.00648.x.

Abstract

Health-related quality of life (HRQoL) and sleep quality (SQ) were impaired in patients with end-stage renal disease (ESRD). The impairment of both HRQoL and SQ and being in a depressive mood were found to be associated with increased morbidity and mortality in dialysis patients. We aimed to investigate the association between SQ, HRQoL, and depression, and to define independent predictors of SQ and depression in peritoneal dialysis (PD) and hemodialysis (HD) patients. Ninety HD patients (41 females, 49 males with mean age 50 ± 15.7 years) and 64 PD patients (27 females, 37 males with mean age 52.4 ± 15.3 years) receiving renal replacement therapy for at least 3 months were screened for the assessment of SQ, HRQoL, and depression in this cross-sectional study. A modified postsleep inventory, Short Form of Medical Outcomes Study (SF-36) and Beck depression inventory (BDI) were applied to all patients for evaluating SQ, HRQoL, and depression, respectively. HD and PD patients had similar total SQ scores. Physical and mental component scale of HRQoL were found to be significantly higher in HD patients (p < 0.001). PD patients were found to be much more in depressive mood when compared with HD patients (p < 0.001). Independent predictors of depression in patients were mental component scale of HRQoL, gender (being female), and dialysis modality (being PD patient). Physical component scale was also found to be an independent predictor of SQ. This study showed that despite similar SQ scores between two groups, HD patients had better HRQoL and less depression than PD patients.

摘要

终末期肾病(ESRD)患者的健康相关生活质量(HRQoL)和睡眠质量(SQ)受损。HRQoL和SQ受损以及抑郁情绪与透析患者发病率和死亡率增加相关。我们旨在研究SQ、HRQoL和抑郁之间的关联,并确定腹膜透析(PD)和血液透析(HD)患者中SQ和抑郁的独立预测因素。在这项横断面研究中,对90例接受肾脏替代治疗至少3个月的HD患者(41例女性,49例男性,平均年龄50±15.7岁)和64例PD患者(27例女性,37例男性,平均年龄52.4±15.3岁)进行了SQ、HRQoL和抑郁评估筛查。分别应用改良的睡眠后问卷、医学结局研究简表(SF-36)和贝克抑郁量表(BDI)对所有患者评估SQ、HRQoL和抑郁。HD和PD患者的总SQ得分相似。发现HD患者的HRQoL身体和心理成分量表显著更高(p<0.001)。与HD患者相比,发现PD患者抑郁情绪更多(p<0.001)。患者抑郁的独立预测因素为HRQoL心理成分量表、性别(女性)和透析方式(PD患者)。身体成分量表也被发现是SQ的独立预测因素。这项研究表明,尽管两组之间SQ得分相似,但HD患者的HRQoL优于PD患者,且抑郁程度更低。

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