六甲铵和潘必定的外周作用。
The peripheral action of hexamethonium and of pentolinium.
作者信息
MANTEGAZZA P, TYLER C, ZAIMIS K
出版信息
Br J Pharmacol Chemother. 1958 Dec;13(4):480-4. doi: 10.1111/j.1476-5381.1958.tb00242.x.
Abstract
The influence of hexamethonium and pentolinium on the responses of certain peripheral effector cells to adrenaline, noradrenaline or postganglionic stimulation was studied in the cat. The actions of adrenaline and noradrenaline on the blood vessels of a limb and of adrenaline and postganglionic stimulation on the nictitating membrane were increased after the administration of hexamethonium and pentolinium. This effect was considered to be due to sensitization of the peripheral effector cells. The possible significance of these findings is discussed.
摘要
在猫身上研究了六甲铵和潘托铵对某些外周效应细胞对肾上腺素、去甲肾上腺素或节后刺激反应的影响。给予六甲铵和潘托铵后，肾上腺素和去甲肾上腺素对肢体血管的作用以及肾上腺素和节后刺激对瞬膜的作用增强。这种效应被认为是由于外周效应细胞的致敏作用。讨论了这些发现的可能意义。
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