WILSON A T
J Exp Med. 1959 Mar 1;109(3):257-70. doi: 10.1084/jem.109.3.257.
Evidence is presented showing that the surface configuration of Group A streptococcal colonies depends largely on whether or not the cocci form a capsule. Strains which form capsules during growth on agar produce mucoid or matt colonies. Strains that do not form capsules during growth on agar produce glossy colonies. Whether or not M antigen is formed by the growing cocci appears to have no direct effect on surface configuration of the colony, although there is an indirect and partial association between M production and the mucoid-matt variant state and between M deficiency and the glossy variant state.
有证据表明,A 组链球菌菌落的表面形态在很大程度上取决于球菌是否形成荚膜。在琼脂上生长时形成荚膜的菌株产生黏液状或粗糙的菌落。在琼脂上生长时不形成荚膜的菌株产生光滑的菌落。生长中的球菌是否形成 M 抗原似乎对菌落的表面形态没有直接影响,尽管在 M 抗原产生与黏液状 - 粗糙变异状态之间以及 M 抗原缺乏与光滑变异状态之间存在间接和部分关联。