WILKINS M H, ZUBAY G
J Biophys Biochem Cytol. 1959 Jan 25;5(1):55-8. doi: 10.1083/jcb.5.1.55.
X-ray diffraction photographs of a nucleoprotein preparation from Escherichia coli show the A-type pattern of crystalline deoxyribonucleic acid (DNA). This suggests that a large part of the DNA is free from protein. In higher organisms DNA does not exist in this form but is closely bound to protein.
对来自大肠杆菌的核蛋白制剂进行X射线衍射拍照,结果显示出结晶脱氧核糖核酸(DNA)的A型图案。这表明大部分DNA未与蛋白质结合。在高等生物中,DNA并非以这种形式存在,而是与蛋白质紧密结合。