Mignone F, Sardella M L, Clara L, Barrett S, Basano R, Barbero I
III Divisione Universitaria di Pediatria, Università di Torino.
Minerva Pediatr. 1992 Dec;44(12):617-22.
The authors assess the efficacy of gold salt treatment for juvenile rheumatoid arthritis. The study was carried out on 16 children suffering from mono-pauciarticular, polyarticular and systemic arthritis. Treatment consisted of the administration of auranofin alone in a group of 8 children and auranofin associated to corticosteroids in a second group of 8 children. A marked improvement in clinical conditions was observed with slight transitory side effects at follow-up after 12 and 24 months.
作者评估了金盐治疗幼年类风湿性关节炎的疗效。该研究针对16名患有单关节、多关节和全身性关节炎的儿童进行。治疗方法为:一组8名儿童单独服用金诺芬,另一组8名儿童服用金诺芬并联合使用皮质类固醇。在12个月和24个月的随访中,观察到临床状况有显著改善,且伴有轻微的短暂副作用。