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[金盐治疗慢性青少年关节炎的获益与风险比较]

[Comparison of the benefits and risks in the treatment of chronic juvenile arthritis with gold salts].

作者信息

Mesihović H, Trebinjac S, Mesihović S, Buljina A

机构信息

Klinika za djecje bolesti, Prof. dr. Milivoje Sarvan, Sarajevo, Republika Bosna i Hercegovina.

出版信息

Lijec Vjesn. 1991 Nov-Dec;113(11-12):420-2.

PMID:1669615
Abstract

Benefits and risks of gold therapy in patients with juvenile chronic arthritis (JCA) were reviewed. An improvement of laboratory and clinical parameters was observed in eight out of the 16 children of the sample (10 boys and 6 girls). The side effects were noticed in 5 patients, but only in one of these children gold therapy had to be stopped due to alopecia areata. Corticosteroid dose was significantly reduced in 7 out of the 11 patients. It is concluded that gold salts may be effectively applied as primary therapy in children with JCA, with no more risk than in adults.

摘要

对青少年慢性关节炎(JCA)患者进行金疗法的益处和风险进行了综述。在样本中的16名儿童(10名男孩和6名女孩)中,有8名观察到实验室和临床参数有所改善。5名患者出现了副作用,但其中只有一名儿童因斑秃不得不停止金疗法。11名患者中有7名患者的皮质类固醇剂量显著降低。得出的结论是,金盐可有效地作为JCA儿童的主要治疗方法应用,其风险并不高于成人。

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