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多囊卵巢综合征女性的脂质紊乱

Lipid disturbances in women with polycystic ovary syndrome.

作者信息

Bednarek-Tupikowska G, Milewicz A, Bolanowski M, Plamieniak Z, Bohdanowicz-Pawlak A, Amałowicz B

机构信息

Department of Endocrinology, Medical Academy Wrocław.

出版信息

Endokrynol Pol. 1991;42(4):595-601.

PMID:1364511
Abstract

Small but detectable disturbances concerning blood lipid levels manifested by somewhat higher concentrations of LDL-cholesterol and triglycerides as well as higher values of atherogenic indices expressing the ratio of cholesterol present in atherogenic lipoprotein fractions to that present in atheroprotective HDL fraction have been shown to exist in 36 women with polycystic ovary syndrome. HDL-cholesterol concentration was lower in women with polycystic ovary syndrome than in healthy women. The disturbances described above were more pronounced in obese patients. No correlation was found between the disturbances in lipid levels and hormonal disturbances particularly hyperandrogenemia.

摘要

在36名多囊卵巢综合征女性中,已发现存在虽小但可检测到的血脂水平紊乱,表现为低密度脂蛋白胆固醇和甘油三酯浓度略高,以及致动脉粥样硬化指数较高,该指数表示致动脉粥样硬化脂蛋白组分中胆固醇与抗动脉粥样硬化高密度脂蛋白组分中胆固醇的比值。多囊卵巢综合征女性的高密度脂蛋白胆固醇浓度低于健康女性。上述紊乱在肥胖患者中更为明显。未发现血脂紊乱与激素紊乱尤其是高雄激素血症之间存在相关性。

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