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[Toxicokinetic exposure tests for chromium].

作者信息

Georgieva R, Zaprianov Z

出版信息

Probl Khig. 1992;17:152-63.

PMID:1364537
Abstract

In cases of occupational exposure to chromium, very often in the organism enters increased quantitatively or six-valent form of metal, possessing high toxicity, cancerogenic and allergenic effect. Concentrations of the element in urine (CrY), erythrocytes (CrE) and nails (CrH) are chosen as suitable tests for evaluation of the exposure. The studies are performed on 151 exposed and controlled persons. The results received are assessed in view of their accuracy and application for biological control. CrY is appropriate test for evaluation of the near in time exposure. CrH detects the cases of occupational CrH--of increased exposure and deficit. On the basis of the proved dependences dose (CrB)--effect (CrY, CrE, CrH) in exposed workers are recommended BMAC (MAC for Cr = 0.02 mg/m3): CrY-2.3 micrograms/l, CrE-3.6 micrograms/l CrH-2.2 micrograms/g.

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