Parkhomenko A N, Bartashevich L N, Popov E R
Lik Sprava. 1992 Jan(1):55-7.
The authors studied the clinical course of myocardial infarction during the acute period, the central and peripheral hemodynamics, immunological reactivity, dynamic electrocardiography by the Holter method in 107 patients with macrofocal and transmural myocardial infarction. It is concluded that it is rational include into the complex treatment of this condition the silicic enterosorbent "Polysorba". The authors recommend to begin polysorba treatment from the first day of onset of the disease especially in the presence of clinical signs of acute circulatory insufficiency. It is suggested to increase the bioavailability and bioassimilability of medicinal agents using the enterosorbent.
作者对107例大面积透壁性心肌梗死患者在急性期的心肌梗死临床病程、中心和外周血流动力学、免疫反应性以及采用动态心电图监测仪(Holter)方法进行的动态心电图进行了研究。得出结论,将硅酸肠道吸附剂“聚烯吡酮”纳入这种疾病的综合治疗是合理的。作者建议从疾病发作的第一天开始进行聚烯吡酮治疗,尤其是在存在急性循环功能不全临床体征的情况下。建议使用肠道吸附剂提高药物的生物利用度和生物可同化性。