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[经心腔电刺激对急性心肌梗死患者坏死灶大小及中心血流动力学指标的影响]

[The effect of transcardiac galvanization on the size of the necrotic mass and on the central hemodynamic indices in patients with an acute myocardial infarct].

作者信息

Maslov A G, Karpov R S, Metelkin A V, Lychev V G, Vidiakov G E, Shishkin M S, Timofeev A V, Derzoglo G D

出版信息

Ter Arkh. 1994;66(8):19-21.

PMID:7985146
Abstract

The authors examined 110 males and females admitted to hospital within 6 hours since the onset of new macrofocal anterior myocardial infarction running without complications. All the patients underwent transcardiac galvanization (TG) in the initial disease hours. Precardiac mapping, tetrapolar rheography and clinical observation provided evidence on TG course action on the necrosis mass, central hemodynamics and clinical appearance of the disease in the acute and postinfarction periods. TG promoted faster and more marked improvement of cardiac muscle contractility, attaining higher functional level of inotropic myocardial activity up to the disease month 6. This was associated with alleviation of circulatory disorders both at the hospital and postinfarction stage. The response to course TG results from cardioprotective action of constant electric current on ischemic myocardium which limits the zone of the lesion thus reducing early fatal cases number and preventing cardiogenic shock.

摘要

作者对110例新发大面积前壁心肌梗死发病6小时内入院且无并发症的男性和女性患者进行了检查。所有患者在疾病初期均接受了经心腔电刺激(TG)。心前区映射、四极血流图和临床观察为TG在急性和心肌梗死后时期对坏死灶、中心血流动力学和疾病临床表现的作用过程提供了证据。TG促进了心肌收缩力更快、更显著的改善,在疾病第6个月时达到更高的心肌变力活性功能水平。这与住院期间和心肌梗死后阶段循环障碍的缓解有关。TG疗程的效果源于恒定电流对缺血心肌的心脏保护作用,这限制了病变区域,从而减少了早期死亡病例的数量并预防了心源性休克。

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