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[乙型病毒性肝炎患者的脂质过氧化与红细胞膜组成]

[Lipid peroxidation and composition of the erythrocyte membranes in patients with viral hepatitis B].

作者信息

Novitskiĭ G K, Mel'nikova G Iu, Podlevskiĭ A F, Vasil'ev V S

出版信息

Lik Sprava. 1992 Jan(1):79-81.

PMID:1364617
Abstract

A study is presented of lipid peroxidation and composition of lipids in erythrocyte membranes in 39 patients with viral hepatitis B. It was established that the content of free cholesterol, lyzophosphatidylcholins, malonic dialdehyde, lipohydroperoxides showed an increase while the level of phospholipids and antioxidant activity decreased in all patients. In patients with viral hepatitis B cytolytic syndrome the content of phosphatidylcholins and sphingomyelins was reduced while in those with cholestasis syndrome the content of phosphatidylethanolamines was reduced.

摘要

对39例乙型病毒性肝炎患者红细胞膜脂质过氧化和脂质组成进行了研究。结果表明,所有患者的游离胆固醇、溶血磷脂酰胆碱、丙二醛、脂氢过氧化物含量均升高,而磷脂含量和抗氧化活性降低。在乙型病毒性肝炎细胞溶解综合征患者中,磷脂酰胆碱和鞘磷脂含量降低,而在胆汁淤积综合征患者中,磷脂酰乙醇胺含量降低。

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引用本文的文献

1
Hepatitis B and its Relationship With Oxidative Stress.乙型肝炎及其与氧化应激的关系。
Hepat Mon. 2016 Jul 17;16(9):e37973. doi: 10.5812/hepatmon.37973. eCollection 2016 Sep.