Saljukov V B, Lemza S V, Kucher A N, Puzyrev V P
Population Genetics Laboratory, Tomsk Scientific Center of the USSR Academy of Medical Sciences.
Arctic Med Res. 1991;Suppl:545-8.
The variability of plasma cortisol, T3, T4, TSH, and estradiol levels was studied in the North Khanty population genetically adapted to the extreme conditions of the North. Negative linear correlations of T3 and T4 levels with age were obtained. Cortisol, estradiol, and T3 levels showed nonlinear age dependency. T4 concentrations were significantly lower in August than February and November. The highest heritability estimate was shown for estradiol levels (44%). The relationships between genetic markers and hormone concentrations were studied.
对在遗传上适应北方极端条件的汉特人北部人群的血浆皮质醇、T3、T4、促甲状腺激素（TSH）和雌二醇水平的变异性进行了研究。获得了T3和T4水平与年龄的负线性相关性。皮质醇、雌二醇和T3水平显示出非线性年龄依赖性。8月份的T4浓度显著低于2月和11月。雌二醇水平的遗传力估计值最高（44%）。研究了遗传标记与激素浓度之间的关系。
