不同动物的补体与抗体在免疫黏附现象中的关系。
The relationship between complement and antibodies of different animals in the immune-adherence phenomenon.
作者信息
TURK J L
出版信息
Immunology. 1959 Apr;2(2):127-36.
A comparison is made of the titres of complement from different animals when reacting with antisera from different species, in the immune-adherence phenomenon. A failure of reaction between rabbit antibody and horse and pig complement is noted. This may be overcome by the addition of heated guinea pig serum. Whereas a similar failure of reaction between rabbit antibody and horse complement in immune haemolysis is also overcome by the addition of ammonia-treated guinea pig serum, this does not occur in immune-adherence. This is interpreted as meaning that there is a further heat-stable ammonia-sensitive co-factor necessary for immune-adherence in addition to the four components of complement. This co-factor is also inactivated by zymosan. The behaviour of mouse complement in immune-adherence indicates a relative deficiency in C′2 as in immune haemolysis. Conglutinin is shown to inhibit immune-adherence irrespective of the species of complement used.
在免疫黏附现象中，对不同动物的补体与不同物种抗血清反应时的效价进行了比较。发现兔抗体与马和猪的补体之间存在反应失败的情况。添加加热的豚鼠血清可克服这一问题。虽然在免疫溶血中，兔抗体与马补体之间类似的反应失败也可通过添加经氨处理的豚鼠血清来克服，但在免疫黏附中却不会出现这种情况。这被解释为意味着除了补体的四种成分外，免疫黏附还需要一种进一步的热稳定且对氨敏感的辅助因子。这种辅助因子也会被酵母聚糖灭活。小鼠补体在免疫黏附中的行为表明，与免疫溶血一样，C′2相对缺乏。已证明共凝集素可抑制免疫黏附，而与所使用的补体物种无关。
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