免疫黏附研究。II. 人补体的阳离子辅助因子需求
Studies with immune-adherence. II. The cation co-factor requirements of human complement.
作者信息
WOODWORTH H C
出版信息
Immunology. 1962 Jan;5(1):187-94.
Abstract
The value of the method of immune-adherence in studying by direct means the role of cation co-factors in human complement activation is shown. Clear evidence for the specificity of the Ca and Mg requirements is presented. Co partially replaced Mg, but other divalent cations tested did not replace either Ca or Mg. The optimal concentrations of cations useful in the titrations of human complement by immune-adherence are suggested to be 0.0001 M Ca and 0.001 M Mg.
摘要
展示了免疫黏附法在直接研究阳离子辅助因子在人类补体激活中的作用方面的价值。给出了钙和镁需求特异性的明确证据。钴部分替代了镁，但所测试的其他二价阳离子既不能替代钙也不能替代镁。建议免疫黏附滴定人类补体时有用的阳离子最佳浓度为0.0001 M钙和0.001 M镁。
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