Brown E J
Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110.
Infect Agents Dis. 1992 Apr;1(2):63-70.
Phagocytosis is an essential component of host defense against invading pathogens. Although many cell types can ingest particulate material, "professional phagocytes" perform this function much more efficiently than other cells because they express unique membrane proteins and signal transduction mechanisms. This review addresses the current state of knowledge about the process of phagocytosis and its regulation.
吞噬作用是宿主抵御入侵病原体的重要组成部分。尽管许多细胞类型都能摄取颗粒物质,但“专职吞噬细胞”执行此功能的效率比其他细胞高得多,因为它们表达独特的膜蛋白和信号转导机制。本文综述了吞噬作用及其调控过程的当前知识状态。